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Guidelines for screening and management of late and long-term consequences of myeloma and its treatment

Guidelines for screening and management of late and long-term consequences of myeloma and its treatment

A APM apoia a Campanha Março Borgonha, de conscientização sobre o Mieloma Múltiplo, tipo de câncer desconhecido por grande parte da sociedade médica. Embora a prevalência seja maior em idosos, jovens também podem desenvolver a doença. Durante o mês, divulgaremos informações e entrevistas com especialistas em nossas mídias sociais. Acesse o site da campanha e acompanhe nossos canais!

John A. Snowden,Writing Group Chair, Diana M. Greenfield, Jennifer M. Bird, Elaine Boland, Stella Bowcock, Abigail Fisher, Eric Low, Monica Morris and Kwee Yong, Guy Pratt on behalf of the UK Myeloma Forum (UKMF) and the British Society for Haematology (BSH).

Summary

A growing population of long-term survivors of myeloma is now accumulating the ‘late effects’ not only of myeloma itself, but also of several lines of treatment given throughout the course of the disease. It is thus important to recognise the cumulative burden of the disease and treatment-related toxicity in both the stable and active phases of myeloma, some of which is unlikely to be detected by routine monitoring. We summarise here the evidence for the key late effects in long-term survivors of myeloma, including physical and psychosocial consequences (in Parts 1 and 2 respectively), and recommend the use of late-effects screening protocols in detection and intervention. The early recognition of late effects and effective management strategies should lead to an improvement in the management of myeloma patients, although evidence in this area is currently limited and further research is warranted.

Keywords: myeloma, late effects, quality of life, haematopoietic stem cell transplantation, chemotherapy.

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